Splice Ending Explained: The Twisted Conclusion To Vincenzo Natali’s Movie

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Previously known to be a female, Dren has now changed sex, and is a male with a newfound purpose: it wants to breed with Elsa. Killing Gavin and William, Dren pins Elsa to the ground and proceeds to rape her. After Clive dies trying to save his partner, Elsa kills Dren once and for all, and is eventually shown to be carrying its child in Splice’s epilogue. Rather than terminate the pregnancy, Elsa takes a healthy sum from her employer, Newstead Pharmaceuticals, to keep the child; as Dren’s DNA is rich in scientific wonders.

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